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Ultrasound-Guided Percutaneous Cryoablation / Breast Cancer Infiltrating Ductal Carcinoma / Breast Cancer · Interventional Study
ClinicalTrials.gov · August 19, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a planned single-arm interventional study of ultrasound-guided percutaneous cryoablation for localized breast cancer in patients ineligible for or declining surgery. No results have been posted; the study has not yet begun recruitment. The registry record describes the research questions and methods but contains no outcome data.
Interventional, Single Group, Open label, Treatment purpose. Breast Cancer, Breast Cancer - Infiltrating Ductal Carcinoma; Female; age from 18 Years. Intervention: Ultrasound-Guided Percutaneous Cryoablation. n = 50. 1 site: Italy.
This is a planned single-arm interventional study of ultrasound-guided percutaneous cryoablation for localized breast cancer in patients ineligible for or declining surgery. No results have been posted; the study has not yet begun recruitment. The registry record describes the research questions and methods but contains no outcome data.
Sample size of 50 is small and may be insufficient for detecting clinically meaningful differences in safety or efficacy.
The source did not state who this applies to in practice.
This is a study registration with no reported results; enrollment has not yet begun. It describes a planned interventional study of an emerging technique in a limited population.
As stated by the source record.
Quoted from the source exactly as published.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.
Registry record from ClinicalTrials.gov (NCT07775014). This is a study registration, not published results. Lead sponsor: Ospedale Cottolengo. Recruitment status: NOT_YET_RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 50 participants (ESTIMATED). Conditions: Breast Cancer, Breast Cancer - Infiltrating Ductal Carcinoma. Interventions: PROCEDURE: Ultrasound-Guided Percutaneous Cryoablation. Primary outcome measures: Complete Tumor Ablation at 6 Months , 6 months after cryoablation. Brief summary: The goal of this clinical trial is to study cryoablation as a treatment for selected adults with localized breast cancer. Cryoablation uses very low temperatures to destroy the tumor through thin needles placed through the skin under ultrasound guidance. The main questions this study aims to answer are: * Can cryoablation completely destroy the treated breast tumor? * Is the procedure safe and well tolerated? * Can ultrasound and contrast-enhanced mammography be used to monitor the treated area after cryoablation? The study will include participants with breast cancer who cannot undergo surgery or choose not to have surgery, as well as selected postmenopausal participants with small, low-risk breast cancers. Participants will undergo ultrasound-guided cryoablation instead of surgical removal of the breast tumor. They will then have clinical examinations and imaging follow-up, including ultrasound and contrast-enhanced mammography, to assess the treated area over time. A biopsy will be performed if follow-up findings are suspicious or unclear. Other cancer treatments, such as radiation therapy or hormone therapy, will be given when indicated according to standard clinical practice.
Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.