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Obesity / MT2 / MT1 · Interventional Study
ClinicalTrials.gov · September 4, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a completed but unpublished small interventional study registered at ClinicalTrials.gov examining appetite response to time-restricted eating (10-hour window, 7:00–17:00) and meal frequency in participants with obesity. No results are posted in this registry record, so the direction, magnitude or statistical significance of any findings cannot be assessed.
Interventional, Randomized, Crossover, Single masking, Health Services Research purpose. Obesity, Meal Frequency, Appetite, Body Composition, Glycaemic Response, Time-restricted Eating; age from 18 Years; to 65 Years; accepts healthy volunteers. Intervention: weight loss diet 1 (2MPD); weight loss diet2 (5MPD). n = 12. 1 site: United Kingdom.
This is a completed but unpublished small interventional study registered at ClinicalTrials.gov examining appetite response to time-restricted eating (10-hour window, 7:00–17:00) and meal frequency in participants with obesity. No results are posted in this registry record, so the direction, magnitude or statistical significance of any findings cannot be assessed.
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
Clinicians and researchers should await full publication of results before drawing any conclusions about time-restricted eating or meal frequency effects on appetite or metabolic health. This registry entry documents study design only and carries no evidence of efficacy or harm.
This is a completed small interventional study (n=12) examining appetite response to time-restricted eating and meal frequency, with no results posted in the registry record.
As stated by the source record.
Quoted from the source exactly as published.
Clinicians and researchers should await full publication of results before drawing any conclusions about time-restricted eating or meal frequency effects on appetite or metabolic health. This registry entry documents study design only and carries no evidence of efficacy or harm.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.
Registry record from ClinicalTrials.gov (NCT07805291). This is a study registration, not published results. Lead sponsor: University of Aberdeen. Recruitment status: COMPLETED. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 12 participants (ACTUAL). Conditions: Obesity, Meal Frequency, Appetite, Body Composition, Glycaemic Response, Time-restricted Eating. Interventions: OTHER: MT1; OTHER: MT2. Primary outcome measures: The participant's appetite response on the test day (day 3rd, 7th, 17th, and 21st) , On test days recorded at timepoints 0, 30, 60, 90, 120, 150 and 180 minutes. On all study days recorded hourly during waking hours. The straight line is 100 mm long, left side indicates low symptoms.. Brief summary: Obesity is one of the largest worldwide health problems. There are increasing rates of overweight and obesity, and in recent years, worldwide the percentage of overweight and obesity among adults now exceeds 1.9 billion and 650 million, respectively. Overweight and obesity are associated with an increase risk of type 2 diabetes (T2D), coronary heart disease, hypertension and other non-communicable diseases. There are multiple nutritional causes for obesity, including both the type and amount of food consumed. Other non-nutritional factors can be just as important to influence body mass, such as the number of meals eaten, which is termed meal frequency. The changing food environment influences calorie consumption, such as increased food variety, increased availability and food processing, a nocturnal lifestyle that disrupts the circadian clock, meal timing and frequency, irregular meal patterns, and prolonged duration of eating during the day. This results in increased food and beverage consumption throughout the day. Meal frequency is commonly defined as, 'the number of foods or drinks a person consumes in one day. Meals and snacks are less clearly defined. Meal is defined as any food providing≥ 50 kcal and separated by more than one hour. In most cultures, the name meal is given to the three eating episodes in a day: breakfast, lunch, and dinner; or breakfast, brunch, lunch, supper, and dinner. In this study, the investigators will use the definition of "breakfast, brunch, lunch, supper, and dinner", but it will be on restricted time: 10 hours eating and 14 hours fasting (from 7:00 to 17:00) and one type of diet (high protein diet). Other researchers have defined meals by the time of the day, such as early and late breakfast, lunch and dinner intake. These definitions differ according to culture. Other researchers have defined meals based on timing, such as (6:00 am -10:00 am), (12:00 pm - 3:00 pm), and (6:00 pm - 9:00 pm). Some studies have highlighted that there are factors that affect the number of meals which a person consumes. Eating a high amount of energy during breakfast helps to feel full for a longer period. Time of eating and duration of eating or not eating. The type of macronutrient intake; for example, high protein (HP) intake reduces ad libitum energy intake. The number of meals eaten per day; some studies have confirmed that consuming small frequent meals is better for healthy weight and appetite control in the general population, compared to consuming one huge meal a day. This can assist control of appetite and plasma glucose concentrations. On the other hand, recent research has indicated that consuming (≥6 meals/day) increases disease risk significantly more than consuming (1-2 meals/day). Some researchers believe that there is no relationship between meal frequency and body weight.
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