Life sciences · Interventional Study
ClinicalTrials.gov · October 21, 2026
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Interventional Study.
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Registry record from ClinicalTrials.gov (NCT05226078). This is a study registration, not published results. Lead sponsor: Abramson Cancer Center at Penn Medicine. Recruitment status: ACTIVE_NOT_RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 64 participants (ACTUAL). Conditions: Chronic Insomnia, Cancer-related Problem/Condition, Cancer-Related Syndrome. Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia. Primary outcome measures: Recruitment , Baseline to End of Treatment (Up to 12 weeks); Adherence , Baseline to End of Treatment (Up to 12 weeks); Treatment Acceptability , End of Treatment; Retention , Baseline to End of Treatment (Up to 12 weeks). Brief summary: Cancer-related fatigue (CRF) and insomnia are prevalent among cancer patients and have been linked to de-creases in quality of life and poorer overall survivorship. Currently, the mechanisms underlying CRF are not well understood, which has led to treatments that are only moderately effective. In addition, when compared to CBT-I in the general population, the treatment outcomes in CBT-I with cancer patients are subpar and, as such, this study will evaluate whether dose of CBT-I is effective in ameliorating CRF.