JUL 28, 2026 · JOURNAL ARTICLE
Morning influenza vaccination elicits superior antigen-specific immune responses in adults aged 60-85 years 2256881
The Journal of Immunology
Randomized controlled trial with pre-specified primary endpoints (antibody and T-cell responses) in a well-defined older adult population shows statistically significant morning vaccination advantage, though T-cell effect did not reach significance.
Reported
p-value (morning vs 11:40-14:20 a…0.005
p-value (morning vs 14:20-17:00 a…0.009
p-value (generalized additive mix…0.012