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Xiaoshan Shen

Affiliated Hospital of Liaoning University of Traditional Chinese Medicine

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AUG 26, 2026 · JOURNAL ARTICLE

Comparative efficacy and cognitive safety of bifrontal versus bitemporal electroconvulsive therapy in adolescents with major depressive disorder: a retrospective cohort study

Frontiers in Psychiatry

A well-conducted retrospective cohort study with adequate sample size and multivariate adjustment showing safety advantages (fewer memory complaints, shorter recovery time) for bifrontal ECT in adolescents, though efficacy was equivalent and cognitive assessment was limited to subjective measures.

PromisingXiaolu Chen Hao Yu Yifan Yang

Reported

BF response rate85.6%

BT response rate82.1%

Response rate comparison p-valuep=0.478

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