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Researcher

David Gonzalez-Martinez

University of Pennsylvania

1 development in the corpus

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AUG 10, 2026 · JOURNAL ARTICLE

Suppression of EGFR signaling and drug-induced potentiation are widespread features of oncogenic RTK fusions

Proceedings of the National Academy of Sciences

Mechanistic cell-based study establishing a signaling principle in cancer cells; proposes a model for RTK fusion behavior but lacks clinical outcome data or in vivo validation needed to guide practice.

Hypothesis-GeneratingSofia Wissert Yuzhi Gao Lung Cancer Treatments and Mutations

Reported

RTK fusion prevalence in cancers~5%

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