AUG 7, 2026 · REVIEW
EFFICACY OF GLP-1 RECEPTOR AGONISTS ON GLYCAEMIC CONTROL AND WEIGHT REDUCTION IN TYPE 2 DIABETES MELLITUS: A SYSTEMATIC REVIEW OF RANDOMIZED CONTROLLED TRIALS
The Indonesian Journal of General Medicine
Systematic review of 32 RCTs with 29,958 participants demonstrating consistent, clinically significant HbA1c reduction (−0.5% to −1.75%, all p<0.001) and weight loss across diverse comparators, with low risk of bias in 23 studies and GRADE-assessed certainty.
Reported
Number of RCTs included32
Total participants29,958
HbA1c reduction range versus plac…−0.5% to −1.75%