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Xiaoyu Xie

National Center for Drug Screening

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AUG 9, 2026 · JOURNAL ARTICLE

A Light-ControlledDNA Nanoclaw Machine: IntegratedMultiplexed Recognition, Spatiotemporally Programmable Therapy, andReal-Time Electrochemical Signaling for Precision Receptor Regulation

Analytical Chemistry

This is an early-stage proof-of-concept study of a novel nanodevice design using in vitro cell culture; it demonstrates feasibility and mechanism but provides no clinical efficacy data, animal studies, or comparison to existing therapeutics.

Hypothesis-GeneratingJiabo Wang 夏国玺 Minglei Zhang

Study details

InterventionLight-gated DNA nanoclaw machine (L-DNM) wi…

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