SEP 6, 2026 · JOURNAL ARTICLE
The potential impact of H1 antihistamines on clinical outcomes in NSCLC patients undergoing EGFR‐TKIs treatment
British Journal of Clinical Pharmacology
Retrospective cohort study with adjusted hazard ratios showing substantial associations between H1-antihistamine use and improved TTF and mortality in NSCLC patients on EGFR-TKIs, but observational design precludes causal inference and requires prospective confirmation.
Reported
Treatment failure hazard ratio (a…0.61
Treatment failure 95% CI0.53–0.71
Treatment failure p-value<.001