SEP 9, 2026 · JOURNAL ARTICLE
A dual-site oral nanovaccine programs anti-colorectal tumor immunity from small intestinal priming to large intestinal boosting
Nature Communications
This is a mechanistic proof-of-concept study in a preclinical model demonstrating a novel nanovaccine strategy; it lacks human data, phase classification, or clinical endpoints needed for stronger evidence grading.
Study details
DesignPreclinical mechanistic study in animal tum…
InterventionOral administration of DPML@OVA-CpG nanovac…
ComparatorPD-L1 antibody therapy and traditional sing…