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AD + SHR + placebo LT and extended-release melatonin 2mg

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AUG 12, 2026 · PHASE 3 TRIAL

Efficacy of Chronotherapeutic Combination for Major Depressive Episode With Insomnia

ClinicalTrials.gov

This is a study registration describing a planned Phase 3 RCT with no reported results; the trial is actively recruiting and no outcome data are available.

PreliminaryMajor Depressive Disorder (MDD) With Insomnia NCT07120880 AD + SHR + active LT and extended-release melatonin 2mg

Reported

Planned sample size184

Study phasePhase 3

Primary outcome measureChange in Montgomery-Åsberg Depression Rati…

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