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Retrospective cohort study with objective image-analysis methods showing WBDK biofilm-matrix quantification achieves AUC 0.921 for 90-day wound healing, but lacks prospective validation, control arm, and real-world implementation testing.
Preclinical in vitro and in vivo study of a novel prodrug showing proof-of-concept mitochondrial targeting and selectivity, but lacking human trials, quantified efficacy metrics, or comparative clinical outcome data.