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This is a narrative review surveying emerging CRISPR applications in antiviral therapy and diagnostics, synthesizing concepts and potential rather than reporting original data or clinical evidence.
A systematic review of CRISPR delivery strategies characterizing methods, principles, and comparative limitations to guide selection of delivery systems for different applications.
Single-isolate laboratory study characterizing a novel phage and resistance mechanisms with in vitro and insect model validation, but lacking human clinical data or comparative efficacy trials.
Mechanistic in vitro study using CRISPR-Cas9 gene editing to explore rcnB function in a single bacterial strain; raises questions about colistin resistance mechanisms rather than establishing clinical evidence.
This is a narrative review article synthesizing engineering strategies for bacterial therapeutics without presenting original empirical data or meta-analyzed outcomes.