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HU Xie-fei

Chongqing Three Gorges Central Hospital

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SEP 8, 2026 · JOURNAL ARTICLE

CRISPR-Based Diagnostic Assay for Point-of-Care Detection of Methicillin-Resistant Staphylococcus aureus in patients with Bloodstream Infections

Acs Sensors

A prospective multicenter clinical evaluation demonstrating 100% sensitivity for S. aureus detection in 350 patients with suspected bacteremia, but limited by small MRSA case numbers (n=8) and lack of specificity data, requiring confirmation in larger MRSA-enriched cohorts before clinical implementation.

PromisingYu Liu Haobo Huang Jing-Song Xu

Reported

Sample size350

S. aureus-positive cases detected20

MRSA-positive cases detected8

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