SEP 10, 2026 · JOURNAL ARTICLE
Panduratin A Induces Caspase-Dependent Apoptosis and G1-Associated Cell-Cycle Arrest and Enhances TNF-α-Associated Cytotoxicity in NSCLC Cells
Biomolecules
In vitro mechanistic study in two cell lines showing PA-induced apoptosis and cell-cycle arrest; no animal models, clinical outcomes, or quantified effect sizes reported; authors themselves call for further validation in more disease-relevant models.
Study details
DesignUncontrolled in vitro cell biology study
InterventionPanduratin A (PA), a chalcone from Boesenbe…
ComparatorSingle-agent treatment (PA alone or TNF-α a…