AUG 12, 2026 · JOURNAL ARTICLE
Mitoxantrone synergies with tigecycline against Klebsiella pneumoniae
Microbiology Spectrum
Mechanistic and proof-of-concept work in vitro and in a murine model identifying a drug repurposing opportunity; lacks human efficacy data and clinical validation needed to support practice change.
Study details
DesignMechanistic and exploratory in vitro and in…
InterventionMitoxantrone alone and in combination with…
ComparatorTigecycline alone; untreated controls impli…