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Researcher

Liangdong Sun

Tongji University

1 development in the corpus

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AUG 12, 2026 · JOURNAL ARTICLE

Proteogenomic characterization of pulmonary large-cell neuroendocrine carcinoma identifies molecular features and therapeutic strategy

Science Advances

Proteogenomic characterization study identifying molecular subtypes and proposing IL-33 as a therapeutic target, with preclinical validation in animal models but no clinical efficacy data in patients.

Hypothesis-GeneratingLung Cancer Research Studies Lele Zhang Neuroendocrine Tumor Research Advances

Reported

Sample size107

Pure LCNEC cases81

Combined LCNEC cases26

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