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Ying Zhi

Department of Clinical Pharmacy, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, School of Pharmaceutical Sciences & Institute of Materia Medical, Shandong First Medical Universi

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JUL 9, 2026 · JOURNAL ARTICLE

A visualizable mitochondrial-targeted Chlorambucil prodrug for enhancing anti-hepatoma efficacy.

Pharmaceutical Science Advances

Preclinical in vitro and in vivo study of a novel prodrug showing proof-of-concept mitochondrial targeting and selectivity, but lacking human trials, quantified efficacy metrics, or comparative clinical outcome data.

PreliminaryHepatocellular Carcinoma Liwei Shao Guojun Pan

Study details

DesignPreclinical in vitro and in vivo explorator…

InterventionBPA-CLB: a structurally derivatized chloram…

ComparatorNot explicitly stated; unmodified chlorambu…

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