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Yizhen Li

St. Jude Children's Research Hospital

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SEP 2, 2026 · JOURNAL ARTICLE

Multimodal analysis of CD38 in T-cell Acute Lymphoblastic Leukemia Identifies Combinatorial Therapeutic Strategies

Blood

Multimodal mechanistic profiling identifying potential CD38-driven pathways and rational combinations in T-ALL, supported by preclinical models and transcriptomic associations, but lacking clinical outcome data.

Hypothesis-GeneratingTori Fuller Jason Xu Rawan Shraim

Reported

Primary tumors analysed by bulk R…1,335

Primary samples analysed by flow…150

Cases analysed by CITE-sequencing40

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