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A narrative review synthesizing evidence on evolving TMS protocols and precision approaches across psychiatry and neurology, without formal meta-analysis or risk-of-bias assessment, positioned as expert synthesis for clinicians navigating emerging practice domains.
A well-conducted retrospective cohort study with adequate sample size and multivariate adjustment showing safety advantages (fewer memory complaints, shorter recovery time) for bifrontal ECT in adolescents, though efficacy was equivalent and cognitive assessment was limited to subjective measures.
A single-centre cross-sectional study identifying catatonia prevalence and predictive factors in adolescents with ASD using validated diagnostic criteria, with a modest effect size (Nagelkerke R² = 0.26) that requires confirmation in larger, prospective cohorts.
Uncontrolled retrospective case series with universal polypharmacy in a small sample (n=28) showing symptom improvement but unable to isolate lurasidone's independent contribution; authors explicitly acknowledge these limitations and call for prospective controlled studies.
A single uncontrolled case report describing clinical and ethical decision-making in one patient; no comparative data, outcome measurements, or generalizable evidence on treatment efficacy.