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Heather M Wilkins

Department of Neurology, University of Kansas Medical Center, Kansas City, KS, USA; University of Kansas Alzheimer's Disease Research Center, Kansas City, KS, USA; Department of Biochemistry and Molecular Biology, University of Kansas Medic

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JUL 30, 2026 · JOURNAL ARTICLE

A combined stimulus of acute fasting and exercise modulates hippocampal mitochondrial quality control in healthy mice.

Cellular Signalling

Mechanistic study in healthy mice using a single acute intervention with surrogate endpoints (mitochondrial markers, proteomics, autophagy flux) and no clinical outcome, requiring confirmation in larger and human cohorts.

PreliminaryBrittany Hauger Keith Smith Colton Lysaker

Reported

LC3-II responsesignificantly increased in FEx group only f…

Complex IV activityincreased post-FEx in females

Time to tissue harvest4 hours after treatment

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