AUG 17, 2026 · JOURNAL ARTICLE
Engineered bacteria as exogenous organelle mimics restore PTEN and p53 tumor suppressor functions for cancer therapy
Nature Communications
This is a proof-of-concept study in murine melanoma using a novel engineered bacterial platform with surrogate endpoints; efficacy and safety in humans remain untested.
Reported
Tumor inhibition94.9%
Survival outcomeall treated mice