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Liangsen Teng

Liuzhou Maternal and Child Health Hospital

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AUG 24, 2026 · JOURNAL ARTICLE

Integrated multi-omics analysis and functional experiments reveals PPAP2C as a potential prognostic biomarker and therapeutic target in breast cancer

Frontiers in Pharmacology

Integrative multi-omics study with confirmatory survival analyses across multiple cohorts and mechanistic validation in TNBC cells and xenografts, but lacks clinical trial evidence and therapeutic efficacy data in vivo.

PromisingLihang Cen Shuguang Zuo Xiaoxi Lin

Reported

PPAP2C upregulation across cancer…upregulated in 16 cancers, downregulated in…

PPAP2C protein positivity in tumo…94.7%

PPAP2C protein positivity in adja…59.7%

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