SEP 12, 2026 · JOURNAL ARTICLE
Association of immune-related adverse events with early tumor shrinkage, depth of response, and survival outcomes in advanced gastric cancer treated with immune checkpoint inhibitors
BMC Cancer
A retrospective single-centre cohort of 49 patients with a clear association between irAEs and improved OS and PFS, but limited by small sample size, single-institution design, and lack of a randomized comparator, requiring confirmation in prospective or larger studies.
Reported
irAE incidence21/49 (42.9%)
Grade ≥3 irAE incidence6/49
Overall survival hazard ratio (ir…0.37