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Shuran Bian

Capital University of Physical Education and Sports

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SEP 7, 2026 · REVIEW

Effects of Nutritional Supplements on Inflammatory Biomarkers in Overweight and Obese Adults: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials

Nutrients

Systematic review and network meta-analysis of 60 RCTs with prespecified methodology, confidence assessment, and consistent directness to inflammatory biomarkers in the target population, though based on surrogate endpoints rather than clinical outcomes.

Strong EvidenceDong Zhang Ailing Liu Zhize Zhou

Reported

Number of trials included60

Green tea extract effect on IL-6MD = −2.57, 95% CI [−3.99, −1.15]

Curcumin effect on IL-6MD = −1.75, 95% CI [−2.74, −0.76]

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