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Gyeong-Won Lee

Gyeongsang National University Hospital

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AUG 10, 2026 · JOURNAL ARTICLE

Early On-Treatment Host Fitness Dynamics Refine Prognostic Stratification in Advanced NSCLC Receiving First-Line Immunotherapy

Cancer Research and Treatment

Prospective multicenter trial of 441 patients shows early on-treatment PNI refines prognosis in advanced NSCLC on immunotherapy with statistically significant associations for PFS and OS, but uses a surrogate nutritional biomarker rather than direct clinical intervention.

PromisingLung Cancer Research Studies Dong-Wan Kim Il Hwan Kim

Reported

Sample size (paired measurements)441

PNI cutoff50.5

6-month response maintenance OR (…0.40

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