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Researcher

Yang Xiao

University of Shanghai for Science and Technology

1 development in the corpus

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SEP 9, 2026 · JOURNAL ARTICLE

Discovery of tepotinib as a novel LY75-targeting small-molecule inhibitor with anti-tumor activity in ovarian cancer via virtual screening

Journal of Ovarian Research

Preclinical discovery study using virtual screening and in vitro/xenograft models without clinical data; identifies a candidate compound but requires clinical validation.

PreliminaryWei Xia Lung Cancer Treatments and Mutations Ovarian Cancer Diagnosis and Treatment

Reported

IC₅₀ (SKOV3 cells)16.31 µM

IC₅₀ (OVCAR-8 cells)18.91 µM

Kinetic K_D (tepotinib–LY75 bindi…2.52 µM

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