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Marie Fernandes

CNR de la Résistance aux Antibiotiques

1 development in the corpus

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SEP 8, 2026 · JOURNAL ARTICLE

Targeting Both Oncogenic Signaling and Dependence Receptor Function is Required to Fully Suppress MET Exon 14 Skipping-Driven tumorigenesis

Cancer Research

Mechanistic study using genome editing and mouse models to propose a novel oncogenic mechanism; lacks clinical trial data or human efficacy evidence for therapeutic translation.

Hypothesis-GeneratingAgathe Laratte Sonia Paget Rémi Tellier

Study details

DesignMechanistic study with genome editing and m…

InterventionGenome editing to remove caspase cleavage s…

ComparatorIndividual mutations of caspase or CBL site…

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