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Ethan D. Shin

Memorial Sloan Kettering Cancer Center

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SEP 7, 2026 · JOURNAL ARTICLE

Do not try this at home: patterns and outcomes of radiation dose de-escalation in p16-positive oropharyngeal carcinoma

Frontiers in Oncology

Large national cohort study with hard clinical outcome (overall survival) showing inferior outcomes with dose de-escalation, aligning with recent randomized evidence and supporting current standard-of-care dosing.

Strong EvidenceAsher J. Shin Jung Julie Kang Sean McBride

Reported

Total sample size14869

Patients receiving dose de-escala…1119 (7.5%)

Three-year OS with DDRT82.1%

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