AUG 13, 2026 · JOURNAL ARTICLE
Efficacy and Safety of Adjusting Antimicrobial Therapy in Episodes of Fever and Neutropenia Catalogued as Fever of Unknown Origin in Children with Cancer: A Randomized Clinical Trial
Antibiotics
Rigorous multicenter randomized noninferiority trial with adequate sample size and clear primary endpoint result showing equivalence between strategies, directly addressing a clinically relevant question in pediatric cancer care.
Reported
Primary endpoint: uneventful reso…106/111 (96%)
Primary endpoint: uneventful reso…114/120 (95%)
Relative risk1.01