SEP 3, 2026 · JOURNAL ARTICLE
Hypoadiponectinemia does not enhance anxiety-like behaviour in a lean PCOS-like mouse model
Scientific Reports
A mixed mechanistic study combining human observational data with a targeted animal model, showing a significant human-animal disconnect that narrows but does not resolve the hypothesis about adiponectin and anxiety in PCOS.
Reported
Sample size (women with PCOS)179
Sample size (control women)228
Adiponectin reduction in APNhet P…65%