AUG 11, 2026 · JOURNAL ARTICLE
EP300‐Mediated MTF1‐K218 Lactylation Buffers AR‐Driven Copper Overload to Suppress Cuproptosis in Castration‐Resistant Prostate Cancer
Advanced Science
Mechanistic study in cell and animal models identifying a pathway by which AR-driven copper buffering might be exploited; lacks clinical trial data or human outcome evidence.
Study details
InterventionMTF1 disruption to collapse copper bufferin…