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François Gernier

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AUG 13, 2026 · JOURNAL ARTICLE

Scalp cooling versus standard cold-cap in preventing chemotherapy-induced alopecia in patients with localized breast cancer: ICELAND protocol, a randomized controlled trial and economic evaluation

PLOS One

This is a protocol paper describing a planned phase III RCT; no results are reported, only study design and endpoints.

PreliminaryJustine Lequesne Laetitia Gigan Bénédicte Clarisse

Reported

Planned sample size196

Randomization ratio1:1

Primary endpoint definitionProportion of patients with NCI-CTCAE v5.0…

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