AUG 10, 2026 · JOURNAL ARTICLE
Deletion of the Salmonella pathogenicity island 2 gene, spiC, in attenuated Salmonella Typhimurium VNP20009 optimizes its potential for bacterial schwannoma therapy
mBio
Preclinical murine model study of engineered bacterial strains with no human data, efficacy endpoints, or quantified effect sizes reported.
Study details
DesignPreclinical genetic characterization and mu…
InterventionAttenuated Salmonella Typhimurium strains:…
ComparatorPBS (phosphate-buffered saline) control; VN…