AUG 14, 2026 · JOURNAL ARTICLE
Five Decades of Mpox in West Africa: History, Epidemiology, Viral Evolution, and Reservoir Ecology (1970–2025)
Zoonotic Diseases
A systematic review synthesizing historical epidemiology and genomic evolution without new primary data or experimental evidence; raises mechanistic questions about cryptic circulation and APOBEC3-mediated hypermutation rather than testing hypotheses.
Reported
Articles synthesized110
Time between clade I and clade II…approximately 3500 years ago
Era of Silence duration1970–2016