JUN 4, 2026 · JOURNAL ARTICLE
Immune response to rotavirus vaccines in low- and middle-income countries: Challenges and perspectives.
Human Vaccines & Immunotherapeutics
A narrative review synthesizing current knowledge on rotavirus vaccine immunology in LMICs and HICs, identifying research priorities but not presenting primary experimental or clinical trial data to support practice changes.
Reported
Vaccine efficacy in high-income c…85–90%
Vaccine efficacy in low- and midd…45–65%
Annual rotavirus deaths in childr…120,000 to 200,000