AUG 8, 2026 · JOURNAL ARTICLE
Multi-Parametric Ultrasound Radiomic Kinetics with Machine Learning Ensemble for Early Prediction of Pathologic Response to Neoadjuvant Chemotherapy in Breast Cancer
Diagnostics
Single-centre prospective cohort with internal cross-validation only, no external validation, using a complex machine learning ensemble on a surrogate radiomic endpoint (week 3 imaging changes) rather than a direct clinical outcome; promising technical result but requires external validation before clinical use.
Reported
Sample size (non-responders)75
Total sample size135
Week 3 mid-band fit change, respo…3.4 ± 0.9 dB