SEP 9, 2026 · JOURNAL ARTICLE
Multi-omics analyses uncover METTL1-mediated tRNA m7G modification–TRADD axis driving breast cancer brain metastasis
Breast Cancer Research
Mechanistic discovery study using multi-omics and cell-based experiments identifying a putative pathway in brain metastasis, without clinical outcome data or Phase 2+ validation in patients.
Reported
Primary findingm7G score higher in BCBrM vs BC; METTL1 upr…
Cell types analysed in scRNA-seq9
Survival associationLow METTL1 expression associated with impro…