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Emil Aagaard Thomsen

Aarhus University

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AUG 18, 2026 · JOURNAL ARTICLE

A genome-wide map of the genetic network in monocytes that regulates type I interferon induction by the cGAS-STING pathway

Science Signaling

Genome-wide CRISPR screening in cell lines identifies candidate genes regulating interferon induction, providing mechanistic insights and a resource for future studies but not clinical evidence of efficacy or causation in disease.

Hypothesis-GeneratingJacob Giehm Mikkelsen Jian Zhao David Olagnier

Study details

DesignFunctional genomics discovery study; genome…

InterventionGenome-wide CRISPR knockout screen targetin…

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