AUG 20, 2026 · JOURNAL ARTICLE
Long-term microbiome and clinical effects of a microbiome-guided personalized diet versus low-FODMAP diet in irritable bowel syndrome: A 12-month follow-up randomized controlled trial.
Gut Microbes
A 12-month follow-up RCT with blinded outcome assessment comparing two dietary interventions in IBS, showing sustained clinical benefit with personalized diet but requiring larger trials to confirm durability and microbiome mechanisms.
Reported
IBS-SSS change personalized diet…−78.3 points from baseline
IBS-SSS change low-FODMAP 12 mont…+29.3 points from 6 weeks
Between-group p-value IBS-SSS 12…0.001