Researcher

Shijuan Gao

Collaborative Innovation Centre for Cardiovascular Disorders, The Key Laboratory of Remodeling-Related Cardiovascular Diseases, Ministry of Education, Beijing Anzhen Hospital, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Capi

1 development in the corpus

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MAY 23, 2026 · JOURNAL ARTICLE

Dual-functional poly(disulfide) enables "Once-and-for-all" atherosclerosis therapy via precision hepatocyte base editing.

Biomaterials

Single-arm preclinical study in mouse atherosclerosis model demonstrating proof-of-concept for a novel delivery approach; lacks human data, comparator arm, and quantified effect sizes.

PreliminaryHongying Wang Xiaoping Zhang Danyang Chen

Study details

DesignPreclinical study (mouse model)

InterventionSingle-dose dual-functional poly(disulfide)…