SEP 7, 2026 · JOURNAL ARTICLE
Structural classification of EGFR mutations and its association with TKI efficacy against compound and co-mutations in a Chinese NSCLC cohort: a single-center retrospective analysis
BMC Cancer
A single-center retrospective cohort study with clear findings on EGFR mutation subtypes and TKI sensitivity in a defined population, but limited by retrospective design, lack of survival or clinical outcome detail, and modest sample sizes for the key comparison groups.
Reported
Sample size452
EGFR mutation prevalence53%
Any gene alteration prevalence81.64%