JUL 6, 2026 · JOURNAL ARTICLE
Astragalin from Morus alba L. ameliorates high-fat diet-induced obesity-related metabolic disturbances in mice and is associated with hepatic AMPK/PI3K/AKT signaling.
Journal of Ethnopharmacology
Sound preclinical study in mice demonstrating metabolic benefit of a natural compound via plausible signaling pathways, but lacks human evidence and relies on surrogate endpoints and mechanistic markers rather than clinical outcomes.
Reported
Primary signaling findingsIncreased hepatic AMPK and PI3K/AKT phospho…