JUL 3, 2026 · JOURNAL ARTICLE
Neuropathological and functional impact of astrocyte-derived extracellular vesicles in an aged model of Alzheimer's disease.
Experimental Neurology
An uncontrolled mechanistic study in a transgenic mouse model using human-derived extracellular vesicles as a pooled intervention, with modest neuropathological changes and no primary clinical endpoint, requires confirmation before clinical translation.
Reported
Rotarod motor coordination p-valuep < 0.0001
Follow-up duration6 months
Mouse age at injection6 months