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Zaid N. Al Shirity

University Medical Center Groningen

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SEP 4, 2026 · JOURNAL ARTICLE

Target Attainment and Clinical and Biochemical Parameters Associated with the Pharmacokinetics of 12 Tyrosine Kinase Inhibitors

Clinical Pharmacokinetics

Single-centre retrospective observational study of TDM data identifying associations between TKI concentrations and biochemical parameters, without clinical outcome validation or prospective intervention testing.

PreliminaryAnouk Dontje Esther Broekman Chronic Myeloid Leukemia Treatments

Reported

Sample size309

Total TKI concentration measureme…1237

Target attainment – alectinib74.6%

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