AUG 24, 2026 · JOURNAL ARTICLE
Phage anti-defense genes targeting NAD+ metabolism and DNA replication are associated with a broad host range against Klebsiella pneumoniae.
Virulence
A sound single-centre phage isolation and characterization study with genetic validation in vitro and a single in vivo model, identifying candidate anti-defense genes associated with broad host range; results are real but require confirmation in clinical settings.
Reported
Host range, wild-type phage109
Plaque formation rate in strain p…~60%
Carbapenem-resistant strains lysed58.8%