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Jinrong Hu

School of Biological and Pharmaceutical Sciences, Shaanxi University of Science & Technology, Xi'an, China.

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AUG 4, 2026 · JOURNAL ARTICLE

Context matters in PROTAC design: navigating the trade-off between degradation and developability.

Journal of Enzyme Inhibition and Medicinal Chemistry

This is a narrative review article that synthesizes existing knowledge and proposes a conceptual framework for PROTAC design; it does not present new primary experimental data, clinical outcomes, or empirical validation of its recommendations.

Hypothesis-GeneratingYunfei Zhang Changhua Ke Chengyuan Liang

Study details

DesignNarrative review article

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