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Andrea Feci

Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA.

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JUL 26, 2026 · JOURNAL ARTICLE

Targeting molecular and genetic pathways driving tumorigenesis for precision therapy in colorectal cancer.

Cancer Biology & Therapy

This is a narrative review synthesizing existing knowledge about molecular pathways in colorectal cancer and therapeutic strategies, without presenting new primary data, clinical trials, or original findings to evaluate.

Hypothesis-GeneratingAllison S Doermann Scott A Waldman Molecular Targeted Therapy

Reported

Projected CRC cases, United State…158,850

Projected CRC deaths, United Stat…55,230

Lynch syndrome as proportion of a…5–10%

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