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Jinpeng Ma

Harbin Medical University

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AUG 11, 2026 · JOURNAL ARTICLE

The pre-treatment tumor microenvironment immune status determines Bacillus Calmette-Guerin immunotherapy response in early-stage bladder cancer

Cancer Immunology Research

A mechanistic study identifying a novel immunosuppressive microenvironment biomarker (MFAP2+ CAF) associated with BCG failure in bladder cancer, based on patient tumour analysis with potential for predicting response, but lacking validation in a prospective cohort or clinical trial.

PromisingZe Zhang Zhiping Wang Yingru Wang

Reported

BCG failure rateover half of patients

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