AUG 16, 2026 · JOURNAL ARTICLE
The Mammalian Target of Rapamycin(mTOR) Signaling Pathway and mTOR Inhibitors in Cancer Therapy
Macromolecular Symposia
This is a narrative review of mechanistic pathways and drug development concepts, not a clinical trial or meta-analysis, and raises questions about mTOR inhibitors rather than testing them in humans with measured outcomes.
Reported
Frequency of mTOR deregulationover 30% of malignancies